AdventHealth Makes OpenEvidence Available Across Clinical Roles

AdventHealth is making OpenEvidence available to physicians, nurses, pharmacists, care managers, therapists and other clinical roles across its network, with access integrated into existing electronic health record workflows, the organizations announced on October 1, 2026. The availability begins October 1, 2026.

Access Inside Existing EHR Workflows

The announcement, datelined Altamonte Springs, Florida, states that AdventHealth is working with OpenEvidence to help care teams find current medical evidence more efficiently. The stated purpose is to reduce the time spent searching for information and create more time for meaningful conversations with patients and families.

Access is integrated into clinicians’ existing workflows within the electronic health record system. According to the announcement, the resource makes it easier for clinicians to research medical scenarios using information grounded in peer-reviewed literature and clinical guidelines.

In the announcement’s framing, when patients and families have questions about a diagnosis, treatment or next step in care, they deserve a team that can bring together clinical expertise, the latest medical evidence and an understanding of the whole person.

Guardrails Around Clinical Judgment

“OpenEvidence gives our care teams a practical way to access current clinical evidence as they care for patients,” said Michael Cacciatore, MD, chief clinical officer for AdventHealth. “It can help reduce the time clinicians spend searching for information and create more time for listening, explaining and caring for the whole person. This gives our care teams another resource to use alongside their training, experience and clinical judgment.”

The resource is intended to “support, not replace” the expertise and accountability of AdventHealth clinicians, according to the announcement. Every care decision remains rooted in professional judgment, the patient’s individual circumstances and the relationship between patients, families and their care team.

AdventHealth describes the work as reflecting its approach to innovation: start with a meaningful care need, introduce technology thoughtfully and keep compassion, trust and whole-person care at the center. The stated goal is to help caregivers focus more of their time and attention on the people they serve rather than adopting technology for its own sake.

Prior Health-System Partnerships

The AdventHealth availability follows OpenEvidence partnerships with Penn Medicine, Memorial Sloan Kettering Cancer Center and the University of Texas Medical Branch announced in September 2026.

On September 15, 2026, OpenEvidence and Penn Medicine announced a global partnership to bring AI-powered clinical decision support to more than 10,000 Penn Medicine clinicians across its seven-hospital U.S. health system. The partnership also extends clinical decision support to low- and middle-income countries through the Botswana-UPenn Partnership, a 25-year-old academic health partnership that works alongside the University of Botswana and the Government of Botswana Ministry of Health. The agreement enables Penn Medicine teams to design a tool from the ground up that is built to support the particular considerations of practicing in the region, according to that announcement.

On September 16, 2026, Memorial Sloan Kettering Cancer Center and OpenEvidence announced a partnership integrating OpenEvidence within MSK’s Epic electronic health record workflow and integrating OncoKB, MSK’s precision oncology knowledge base, directly into OpenEvidence for broader use by providers outside MSK. The MSK announcement states that in October 2021, OncoKB became the first and remains the only somatic cancer variant knowledge base to be partially recognized by the U.S. Food and Drug Administration. Through the partnership, OncoKB’s curated, cancer type-specific annotations, including the oncogenic effect, level of evidence and associated therapies for each alteration, will be surfaced within OpenEvidence, within Epic, alongside patient context.

On September 22, 2026, the University of Texas Medical Branch and OpenEvidence announced a collaboration embedding OpenEvidence within UTMB’s electronic health record environment, an integration that went live at UTMB in March. UTMB clinicians access the platform using their standard enterprise credentials and can ask clinical questions in natural language, receiving responses that include citations to medical literature, clinical guidelines and other sources. The UTMB announcement reported that more than half of UTMB clinicians actively use OpenEvidence for clinical decision support, with growth since the March launch in both the number of clinicians using the platform and the volume of clinical queries submitted.